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1

Preparation of tritiated 2,4-diamino-5-adamantyl-6-methylpyrimidine

Sigmund F. Zakrzewski, E. Anthony Evans

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1981

Language:

english

File:

PDF, 343 KB

english, 1981

2

Preparation of tritiated dihydrofolate and its use in the assay of dihydrofolate reductase

Sigmund F. Zakrzewski, Jaakko J. Himberg

Journal:

Analytical Biochemistry

Year:

1971

Language:

english

File:

PDF, 536 KB

english, 1971

3

Phase I clinical trial and human pharmacokinetics of 2,4-diamino-5-adamantyl-6-methyl pyrimidine ethane sulfonate (DAMP-ES): a lipid-soluble antifolate

Patrick J. Creaven, Sigmund F. Zakrzewski, William R. Greco, Stefan Madajewicz, Arnold Mittelman, J. Edson Pontes, Constantine Karakousis, Hiroshi Takita, April Proefrock

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1988

Language:

english

File:

PDF, 641 KB

english, 1988

4

On the specificity of labeling in tritiated folic acid

Sigmund F. Zakrzewski, E. Anthony Evans, Roger F. Phillips

Journal:

Analytical Biochemistry

Year:

1970

Language:

english

File:

PDF, 790 KB

english, 1970

5

Synthesis and biological activity of some 5-(1-adamantyl)pyrimidines. 1

Jonak, James P., Zakrzewski, Sigmund F., Mead, Lawrence H., Hakala, Maire T.

Journal:

Journal of Medicinal Chemistry

Year:

1970

Language:

english

File:

PDF, 403 KB

english, 1970

6

Molecular structures of 2,4-diaminopyrimidine antifolates with antineoplastic activity

Cody, Vivian, Zakrzewski, Sigmund F.

Journal:

Journal of Medicinal Chemistry

Year:

1982

Language:

english

File:

PDF, 956 KB

english, 1982

7

On the enzymic reduction of folic acid by a purified hydrogenase

Sigmund F. Zakrzewski, Charles A. Nichol

Journal:

Biochimica et Biophysica Acta

Year:

1958

Language:

english

File:

PDF, 147 KB

english, 1958

8

Synthesis and antifolate activity of new diaminopyrimidines and diaminopurines in enzymic and cellular systems

Kavai, Ivan, Mead, Lawrence H., Drobniak, Jadwiga, Zakrzewski, Sigmund F.

Journal:

Journal of Medicinal Chemistry

Year:

1975

Language:

english

File:

PDF, 551 KB

english, 1975

9

Synthesis and biological activity of some 5-(1-adamantyl)pyrimidines. 2

Jonak, James P., Zakrzewski, Sigmund F., Mead, Lawrence H.

Journal:

Journal of Medicinal Chemistry

Year:

1971

Language:

english

File:

PDF, 1.29 MB

english, 1971

10

[Methods in Enzymology] Vitamins and Coenzymes Volume 18 || [186] A new preparation of tetrahydrofolic acid

Zakrzewski, Sigmund F.

Year:

1971

Language:

english

File:

PDF, 211 KB

english, 1971

11

[Methods in Enzymology] Vitamins and Coenzymes Volume 18 || [185] A new preparation of dihydrofolic acid

Zakrzewski, Sigmund F.

Year:

1971

Language:

english

File:

PDF, 97 KB

english, 1971

12

Hydrophobic interactions between the 5-alkyl group of 2,4-diamino-6-methylpyrimidines and dihydrofolate reductase

Ho, Yiu K., Zakrzewski, Sigmund F., Mead, Lawrence H.

Journal:

Year:

1973

Language:

english

File:

PDF, 358 KB

english, 1973

13

Synthesis and biological activity of some 5-substituted 2,4-diamino-6-alkylpyrimidines. 3

Jonak, James P., Zakrzewski, Sigmund F., Mead, Lawrence H.

Journal:

Journal of Medicinal Chemistry

Year:

1972

Language:

english

File:

PDF, 533 KB

english, 1972

14

Preparation and Biological Activity of Dihydroaminopterin *

Zakrzewski, Sigmund F., Hakala, Maire T., Nichol, Charles A.

Journal:

Year:

1962

Language:

english

File:

PDF, 574 KB

english, 1962

15

[Methods in Enzymology] Vitamins and Coenzymes Part E Volume 66 || [68] Preparation of tritiated dihydrofolic acid of high specific activity

Zakrzewski, Sigmund F.

Year:

1980

Language:

english

File:

PDF, 238 KB

english, 1980

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